Combined application of Metarhizium anisopliae with other chemical insecticides can improve its efficacy and overcome pest resistance to the chemicals

Metarhizium anisopliae has different action mechnism from other insecticides, thus it has synergistic interaction with others to improve efficacy.
Resistant pests have resistance to chemical insecticides but lose resistance to fungal insecticdes. In fact, any insect pests hardly have resistance to fungal insecticides.