The cotton bollworm (Helicoverpa armigera), belonging to Noctuidae, is one of the most destructive pest insects in agriculture worldwide.
It causes severe damage to plant crops, resulting in massive economic losses. Over the past decades, cotton bollworm has gradually developed resistance against almost all chemical pesticides.
As an effective biological agent (against cotton bollworm, Helicoverpa armigera nucleopolyhedrovirus has been exploited as a biopesticide to control pest insects.